What is hereditary ATTR (hATTR) amyloidosis?
Symptoms of hATTR amyloidosis can progress quickly, leading to significant disability
It runs in the family
hATTR amyloidosis is caused by a mutation or change in the TTR gene. Any child of a parent with this mutation will have a 50% chance of inheriting the mutation. However, this does not necessarily mean that the child will develop the condition. It's important to understand your family health history and speak with your doctor about how hATTR amyloidosis runs in the family.
It affects several parts of
hATTR amyloidosis can affect the nerves, heart, and digestive system, which means individuals may experience a range of symptoms that may not seem related to one another.
It often impacts quality
- Decreased mobility
- Gastrointestinal issues
- Trouble with self-care
- Difficulty performing usual activities
The varying symptoms of
This is not a complete list of symptoms that may be experienced with hATTR amyloidosis.
Adapted from Conceição I, et al. J Peripher Nerv Syst. 2016;21(1):5-9.
ONPATTRO® (patisiran) does not treat all of these symptoms.