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Understanding how hereditary ATTR (hATTR) amyloidosis develops

hATTR amyloidosis is caused by a gene change (mutation) that affects the function of a protein in the body called transthyretin (TTR)

How hATTR amyloidosis develops

How does ONPATTRO® (patisiran) work?

ONPATTRO® (patisiran) decreases the amount of amyloid deposits and may result in fewer symptoms
84%

The average decrease in TTR protein in a clinical study of adult patients treated with ONPATTRO after 18 months